Tinkering with the CAR
Recent work by Michael Gotthardt’s group at the MDC reveals crucial functions for the Coxsackie-adenovirus receptor, or CAR, in the development of the heart, communication between its cells, and the destructive effects of viral infections. The joint study between basic scientists at the MDC and clinical partners at the Franz Volhard Clinic of the Charité, and Fritz Rathjen’s group at the MDC has been published in the Journal of Experimental Medicine, and may yield a new strategy to treat some types of heart disease.
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