Accepted abstracts
Dear authors,
After completing the peer-review process under supervision oft he Board of Directors of CIMT, we would like to inform you now about the accepted abstracts.
Authors whose abstracts are selected for oral presentation will be notified by a separate mail until April 18, 2008.
Abstracts whose authors are not registered via the CIMT website until April 18, 2008, will be rejected.
List of accepted abstracts:
| P01 | Oxidized Mannan Potentiates DNA Vaccine for use in Cancer Immunotherapy Choon Kit Tang, Geoff Pietersz, Vasso Apostolopoulos |
| P02 | A new shared melanoma antigen:an attractive target for future immunotherapy protocols Godet Yann, Agnès Moreau-Aubry, Yannick Guilloux, Amir Khammari, Brigitte Dreno, Francine Jotereau, Nathalie Labarriere |
| P03 | Interferon-alpha enhances anti-tumor effect of chemotherapy in an orthotopic mouse model for pancreatic adenocarcinoma Yifan Zhu, Igor Tibensky, Jan Schmidt, Eduard Ryschich, Angela Märten |
| P04 | Intratumoural injection of the toll-like receptor-2/6 agonist “macrophage-activating lipopeptide-2” in patients with pancreatic carcinoma: a phase I/II trial Jan Schmidt, Thilo Welsch, Dirk Jäger, Peter F. Mühlradt, Markus W. Büchler, Angela Märten |
| P05 | Induction of p53-specific immunity in patients with colorectal cancer vaccinated with a p53 synthetic long peptides vaccine F.M. Speetjens, P.J.K. Kuppen, M.J.P. Welters, F. Essahsah, A.M.E.G. Voet, M.G. Kallenberg, A.R.P.M. Valentijn, J. Oostendorp, L.M. Fathers, Jan W. Drijfhout, C.J.H. van de Velde, C.J. Melief, S.H. van der Burg |
| P06 | Improvement of Median Survival And Disease Stability in DC-Vaccinated Melanoma Patients Correlates with Tumor Cell Lysate-Specific DTH Reaction and Regulatory T Cell decreasing. Mercedes N. López, Cristian Pereda, Gabriela Segal, Leonel Muñoz, Raquel Aguilera, Fermín E. González, Alejandro Escobar, Alexandra Ginesta, Diego Reyes, Rodrigo González, Milton Larrondo, Alvaro Compán, Carlos Ferrada, and Flavio Salazar-Onfray |
| P07 | Double positive (CD4+CD8+) T cells depletion in experimental glioma bearing mice Maciej Lesniak, Abdeljabar El Andaloussi |
| P08 | Immune response induced by therapeutic vaccination with epidermal growth factor (EGF) in NSCLC patients García B, Neninger E, Torres A, Leonard I, Martínez R, Viada C, González G, Lage A, Crombet T and Mazorra Z |
| P09 | The tumor-associated antigen PRAME inhibits cell differentiation by blocking the receptor for retinoic acid (RAR)-signaling in vitro and induces at high frequency specific T cell responses in leukemia patients Jochen Greiner, Lars Bullinger, Krzysztof Giannopoulos, Anita Schmitt, Hartmut Döhner, Michael Schmitt |
| P10 | Immunological and clinical outcome of patients with acute
myeloid leukemia (AML), myelodysplastic syndrome (MDS), multiple myeloma (MM) and chronic lymphocytic leukemia (CLL) vaccinated with 300 or 1000 mcg RHAMM-R3 peptide Michael Schmitt, Anita Schmitt, Krzysztof Giannopoulos, Markus T. Rojewski, Jinfei Chen, Marlies Götz, Gerd Ritter, Sacha Gnjatic, Phillipe Guillaume, Mark Ringhoffer, Martin Bommer, Richard F. Schlenk, Peter Liebisch, Donald Bunjes, Hartmut Döhner, Jochen Greiner |
| P11 | Highly efficient mRNA and siRNA transfection to manipulate normal CD34 positive hematopoietic progenitor cells, mesenchymal stem cells and leukemic cells Jochen Greiner, Markus Wiesneth, Markus Rojewski, Hubert Schrezenmeier, Vinzenz Hombach, Oliver Zimmermann, Hartmut Döhner, Jan Torzewski, Juliane Wiehe, Michael Schmitt |
| P12 | Th1-Cytokine Profile of Monocyte derived Dendritic Cells is achieved best by Maturation with the Inflammatory Cytokine Cocktail plus CD 40 Ligation Timo Buhl, Holger Haenssle, Susanne Knudsen, Ullrich Krueger, Kristian Reich, Christine Neumann |
| P13 | Specific cytotoxic T cells in cancer immunity and autoimmunity Rikke Bæk Sørensen, Mikkel Faurskov, Lone Troelsen, Søren Jacobsen, David Schrama, Jürgen C. Becker, Per thor Straten and Mads Hald Andersen |
| P14 | Increased frequency of double positive CD4CD8 T cells among lymphocytes infiltrating human advanced breast cancers Juliette Desfrançois, Laurent Derré, Murielle Corvaisier, Bernard le Mével, Véronique Catros-Quéméner, Francine Jotereau and Nadine Gervois |
| P15 | Phenotypic and functional properties of regulatory T cells in a mouse model of spontaneous melanoma Silvia Kimpfler, Dirk Schadendorf and Viktor Umansky |
| P16 | Tumour infection by oncolytic reovirus primes adaptive anti-tumour immunity Robin Prestwich, Fiona Errington, Peter Selby, Richard Vile, Alan Melcher |
| P17 | Identification of the tumour-associated antigen hABL908-922 Sabine Höpner, Philipp le Coutre, Olaf Rötzschke |
| P18 | Identification of an HLA-A2-restricted Mcl-1 epitope for anticancer immunotherapy Rikke Sick Andersen, Lynn Wenandy, Rikke Bæk Sørensen, Per thor Straten, Mads Hald Andersen |
| P19 | Effect of Bacille Calmette-Guérin, Purified Protein Derivative on Differentiation and Antigen uptake of Dendritic Cells from PBMC of Cervical Cancer Patients Manickam Alagar, Sivanadham Muthukumaran |
| P20 | see P48 |
| P21 | Identification of novel tumor antigens for γδ T lymphocytes Anita Gomes, Daniel Correia and Bruno Silva-Santos |
| P22 | Recombinant tumor vaccines targeted to CD40 for selective uptake by professional antigen presenting cells Ute Burkhardt, Arjen Sloots, Annemarie Schimpf, Winfried S. Wels |
| P23 | A real-time PCR method to assay the molecular expression of multiple tumor antigens in patient biopsies Brian Weinert, Francesca Milano, Toh Han Chong, Sheila Krishnadath, Mai-Britt Zocca |
| P24 | Targeted induction of tumor cell death by an immunotoxin-like antibody fusion protein carrying human apoptosis-inducing factor Hayat Mahmud, Benjamin Dälken and Winfried S. Wels |
| P25 | Differential expression of IL-17A and IL-17F in the lung of patients affected with lung carcinoma. Ildikó Boross, Roman Karwot, Joachim H. Maxeiner, Petra Scholtes, Hans A. Lehr, Michael Koslowski, Rainer Wiewrodt, Özlem Türeci and Susetta Finotto |
| P26 | The effect of structure modifications on antigen-binding
properties of anti-CD3 recombinant antibodies Anja Feldmann, Holger Bartsch, Cordula Büttner, Michael Bachmann |
| P27 | Activation of T cells against tumors by a novel modular targeting system Anja Feldmann, Holger Bartsch, Michael Bachmann |
| P28 | Combining radio- and immunotherapy: The La protein on irradiated tumor cells as surface target molecule for a universal immunotherapy Claudia Franke, Holger Bartsch, Michael Bachmann |
| P29 | Activation of natural killer cells against tumors by bispecific proteins Slava Stamova, Holger Bartsch, Michael Bachmann |
| P30 | Treatment of experimental melanoma in mouse by living culture mycelium of oyster mushroom, Pleurotus ostreatus: preliminary results M. Saieh, L.Vannucci, V.Šašek, K. Klimešová, P. Rossmann, V. Erban, R. Sovjak, A.Fišerová |
| P31 | RNA-based cancer vaccines Mariola Fotin-Mleczek, Katharina Brauer, Ingmar Hörr, Jochen Probst |
| P32 | Identification of novel CD4+ T cell epitopes from human Tyrosinase-related protein 1 and 2 (TRP-1/-2) upon vaccination of HLA-class II transgenic mice with recombinant Adenovirus followed by combinatorial peptide library screening Wolfram Osen, Mingxia Song, Sabine Soltek, Julia Steitz, Barbara Leuchs, Xuan Duc Ngyuen, Dirk Schadendorf, Annette Paschen |
| P33 | Recombinant antibodies from IgM Type antibodies: Restoring loss of avidity by oligomerization Holger Bartsch, Claudia Franke, Peter Rieber, Michael Bachmann |
| P34 | Treatment of metastatic melanoma by adoptive transfer of ex-vivo expanded polyclonal tumor-specific T-cells preceded by interferon conditioning Els Verdegaal, Inonge van Twillert, Marten Visser, Hannah Wensink, Lien van der Minne, Tamara Rhamwadhdoebé, Conny Hoogstraten, Jeanne van Steijn, Susanne Osanto |
| P35 | T cell responses in prostate carcinoma patients after multi-peptide immunotherapy Melanie Widenmeyer, Heinrich Griesemann, Susan Feyerabend, Reinhild Klein, Sebastian Attig, Jörg Hennenlotter, Patricia Hrstic, Stefan Stevanovic, Markus Kuczyk, Arnulf Stenzl, Cécile Gouttefangeas, Hans-Georg Rammensee |
| P36 | Fine analysis of tumor-infiltrating lymphocyte subsets in renal cell cancer Sebastian Attig, Jörg Hennenlotter, Sven Koch, Gerd Klein, Hanspeter Pircher, Arnulf Stenzl, Graham Pawelec, Hans-Georg Rammensee, Cécile Gouttefangeas |
| P37 | Activated gd T cells- an alternative for antigen specific immunotherapy? Silke Landmeier, Bianca Altvater, Sibylle Pscherer, Lena Varnholt, Anna Hansmeier, Catherine M. Bollard, H. Juergens, Claudia Rossig |
| P38 | 2B4 as a potent immunostimulatory molecule for retargeting NK cell activity against cancer Bianca Altvater, Silke Landmeier, Sibylle Pscherer, Katharina Schweer, Heribert Juergens, Claudia Rossig |
| P39 | Modulation of benzo[a]pyrene-induced immunotoxicity in mice actively immunized with B[a]P-carrier conjugates Nathalie Grova, Mario Schellenberger, Stephanie Willième, Sophie P.B. Farinelle, Claude P. Muller |
| P40 | Human T cells equipped with tumor-reactive TCR optimized in vitro elicit tumor growth control in NOD-SCID mice engrafted with a human melanoma Christina Pfirschke, Diana Knies, Ratna Sari Intan Poendl, Margarete Grabowski, Christoph Huber, Philipp Beckhove, Matthias Theobald, Ralf-Holger Voss |
| P41 | Frequency of IL-17-producing CD4+ T-cells in peripheral blood correlates with clinical response to whole-cell vaccination therapy in prostate cancer patients Evelyna Derhovanessian, Karin Hähnel, Andrea Groeger, Victoria Adams, Stephen Ward, Graham Pawelec |
| P42 | Laser technology for cancer immunotherapy Ph.D. Valerii Kanevskyi, Ph.D. Igor Filchakov |
| P43 | Carcinoembryonic antigen specific but not anti-viral CD4+ T cell immunity is impaired in pancreatic carcinoma patients Elena Tassi, Francesca Gavazzi, Vladimir Senyukov, Renato Longhi, Paolo Dellabona, Marco Braga, Valerio Di Carlo, and Maria Pia Protti |
| P44 | Validation of immunological endpoint assays for detection of cellular and humoral responses to an anti-cea dna vaccine Ann Mander, Steven Harrison, Ferdousi Chowdury, Lindsey Low and Christian Ottensmeier |
| P45 | DNA fusion gene vaccination, delivered with or without in vivo electroporation - a potent and safe strategy for inducing anti-tumor immune responses in prostate cancer Lindsey Low, Ann Mander, Steven Harrison, Tony Williams, Torunn Tjelle, Juan Campos-Perez, Catharine Heath, David Dearnaley, Iacob Mathiesen, Freda Stevenson, Christian Ottensmeier |
| P46 | Combination chemotherapy using cyclophosphamide and fludarabine prior to reconstitution with autologous PBMC and vaccination with autologous tumor and GM-CSF fails to result in long-term reduction of regulatory T cells in lung cancer patients Natasja K. van den Engel, Hauke Winter, Heike Pohla, Dolores J. Schendel, Nina Schupp, Beate Wagner, James Thompson, Tarsem Moudgil, Karl-Walter Jauch, Bernard A. Fox, Rudolf A. Hatz, Dominik Rüttinger |
| P47 | Experimental gene therapy of orthotopic hepatocellular carcinoma: Synergism and expression of IL-12, 4-1BBL and IL-2 from a single adenoviral vector Reinhard Waehler, Marius Schwerg, Harald Ittrich, Lars Mueller, Karim Sultan & Frank Schnieders |
| P48 | Stimulation of mouse and human immune cells by tumor cells expressing multiple immunostimulators Marius Schwerg, Nancy Brewig, Uwe Ritter, Reinhard Waehler, Frank Schnieders & Karim R. Sultan |
| P49 | Dynamics of tumor-specific immune responses in patients affected by metastatic melanoma following vaccination with autologous lymphocytes genetically modified to express the MAGE-3 tumor antigen Raffaella Fontana, Marco Bregni, Arcadi Cipponi, Laura Raccosta, Cristina Rainelli, Daniela Maggioni, Francesca Lunghi, Fabio Ciceri, Sylvain Mukenge, Claudio Doglioni, Didier Colau, Pierre Coulie, Claudio Bordignon, Catia Traversari and Vincenzo Russo |
| P50 | Survivin as potential target-protein for immunotherapy in patients with adrenocortical carcinoma Silviu Sbiera, Sebastian Wortmann, Luitgard Kraus, Tabitha Thamm, Dorothee Kuehner, Sebastian Schmull, Marion Wobser, Jürgen Becker, Patrick Adam, Bruno Allolio, Martin Fassnacht |
| P51 | Adjuvant multi-peptide vaccination in high risk early melanoma patients Paola Filipazzi, Agata Cova, Lorenzo Pilla, Roberto Patuzzo, Chiara Castelli, Andrea Maurichi, Gloria Sovena, Gabrina Tragni, Michele Maio, Giorgio Parmiani, Mario Santinami and Licia Rivoltini |
| P52 | Induction of antigen-specific killing of cells by a high-affinity monoclonal T cell receptor-anti-CD3 fusion protein A. Turner, O. Morteau, D. Williams, K. Adams, A. Gerry, P. Molloy, J. Gavarret, N. Liddy, Y. Li, A. Vuidepot, T. Mahon, N. Pumphrey, N. Lissin, O. Polyakova, R. Ashfield, B. Jakobsen |
| P53 | Cooperation of Toll-like receptor signaling and CD4 T cell help on priming and memory of cytotoxic T-lymphocytes in vivo B. Schmid, N. Hilf, C. Tertilt, M.P. Radsak, H. Schild |
| P54 | The role of CLL - stromal cell interaction in immunotherapy M. Buchner, M. Burger, P. Brantner, G. Prinz, J. Gribben, H. Veelken, K. Zirlik |
| P55 | CD103+ CD8+ regulatory T cells: A new subset of CD8+ regulatory T cells in renal cell carcinoma? Sven Koch, Henrieke Struijk, Si-La Yong, Elena Uss, Sebastian Attig, Jörg Hennenlotter, Arnulf Stenzl, Cécile Gouttefangeas, Rene van Lier and Ineke ten Berge |
| P56 | |
| P57 | Identification and validation of resistance mechanisms to rituximab based therapies in B-cell lymphoma Claudia Stolz, Georg Heß, Patricia S. Hähnel, Florian Grabellus, Sandra Hoffarth, Christoph Huber, Kurt W. Schmid, Martin Schuler |
| P58 | Generation of an antibody-4-1BBL fusion protein for targeted costimulation in tumor immunotherapy with bispecific antibodies Dafne Müller, Katharina Frey, Roland E. Kontermann |
| P59 | Generation and characterization of costimulatory B7-antibody fusion proteins for targeted cancer immunotherapy Agnes Banaszek, Roland E. Kontermann, Dafne Müller |
| P60 | Many antigen presenting cells, or much antigen per presenting cell; studies on priming and expansion of melanA-specific T cells Jan Dörrie, Niels Schaft, Verena Wellner, Chris Wohn, Tanja Schunder, Ina Müller, Eckhart Kämpgen, Gerold Schuler |
| P61 | Reprogramming of bulk T cells with a tumor-antigen specificity by electroporation of RNA encoding chimeric T cell receptors Niels Schaft, Tanja Schunder, Christian Krug, Sabine Reuter, Daniela Kosmides, Hinrich Abken, Michael Kershaw, Eckhart Kämpgen, Gerold Schuler, Jan Dörrie |
| P62 | Electroporation of CD4+ T cells with TCR-encoding RNA
to examine the DC / helper T cell cross-talk Stefanie Hoyer, Katrin Birkholz, Eckhart Kämpgen, Gerold Schuler, Jan Dörrie, and Niels Schaft |
| P63 | New strategies for the impromement of pharmacokinetics of recombinant bispecific antibody molecules for targeted cancer immunotherapy Roland Stork, Kirstin Zettitz, Miriam Rether, Dafne Müller und Roland Kontermann |
| P64 | A fast and sensitive method to clone and functionally validate T cell receptors Christian Hofmann, Katrin Birkholz, Stefanie Hoyer, Birgit Schulz, Verena Wellner, Eckhart Kämpgen, Gerold Schuler, Jan Dörrie, Niels Schaft |
| P65 | Devitalization as a special surgical tumour treatment inducing anti-cancer response – an experimental study in two animal models Vratislav Horak, Alena Moravkova, Jan Strnadel, Jan Hradecky, Dusan Usvald, Luca |
| P66 | Immunotherapy with RNA loaded dendritic cells in an experimental mouse glioma model: the balance between immunogenicity and tolerance Wim Maes, Georgina Galicia, Bert Verbinnen, Louis Boon, Jan Ceuppens, Stefaan Van Gool |
| P67 | Active unspecific immunotherapy of experimental pancreatic carcinoma with bacteria Claudia Maletzki, Michael Gock, Sarah Schuschan, Bernd Kreikemeyer, Joerg Emmrich, Michael Linnebacher |
| P68 | Up-regulated Stat3 and MAPK activities in DCs from a spontaneous melanoma mouse model: a role of tumor-derived factors in tolerogenic DC generation Fang Zhao, Wolfram Osen, Dirk Schadendorf, Viktor Umansky |
| P69 | The role of TGFß signaling in murine models of lung cancer Kinga Soó, Roman Karwot, Joachim H. Maxeiner, Petra Scholtes, Ildikó Boross, Nataliya Zhivkova, Hans A. Lehr, Michael Koslowski, Rainer Wiewrodt, Özlem Türeci, and Susetta Finotto |
| P70 | Phenotypic analysis of primary CD34(high)+ CD38neg leukemic blasts targeted by allogeneic cell therapy in acute myeloid leukemia Anna Jürchott, Eva Distler, Abdo Konur, Eva Wagner, Christoph Huber, Ralf G. Meyer, Wolfgang Herr |
| P71 | Towards reliable in vitro generation and in vivo evaluation of leukemia-reactive CD8+ cytotoxic T lymphocyte clones from healthy donors Eva Distler, Catherine Wölfel, Sylvia Köhler, Marion Nonn, Elke Schnürer, Ralf G. Meyer, Christoph Huber, Thomas Wölfel, Udo F. Hartwig, Wolfgang Herr |
| P72 | In vitro induction and expansion of CD8 positive T cells: a method applicable for the generation of low-frequency antigen specific CD8 positive T cells Agnieszka Wieczorek, Kang-Hun Lee and Lutz Uharek |
| P73 | Spontaneous rejection of GP33-positive Lewis lung carcinoma requires activation of T cells in an IFNAR competent environment Patricia Bach, Susanne Roederstein, Peter Aichele, Ulrike Blohm, Thomas Hinz, Hanspeter Pircher, and Ulrich Kalinke |
| P74 | Intracellular delivery of antigenic peptides and poly(I:C) leads to full dendritic cell maturation, high IL-12 secretion and increased T cell stimulatory capacity Holger Haenssle, Timo Buhl, Petra Riedl, Reinhold Schirmbeck, Karolin Zachmann, Jörg Reimann |
| P75 | HLA ligands in lung cancer A. Neumann, N. Hillen, D. Maurer, H.-G. Rammensee, H. Aebert, S. Stevanovic |
| P76 | Effects of radiofrequency ablation on porcine melanoma and rat sarcoma Vratislav Horak, Jan Strnadel, Alena Moravkova, Milos Kucera, Dusan Usvald, Luca Vannucci, Daniela Planska, Jan Hradecky |
| P77 | Attempts to enhance the efficacy of DNA vaccination by a gene gun with TLR ligands Eva Vajdová, Michal Šmahel |
| P78 | DNA vaccine against WT1 tumor antigen Eva Ouradnikova, Jana Mackova, Vincent Lucansky, Petr Hainz, Michal Smahel, Luda Kutinova and Sarka Nemeckova |
| P79 | Exhaustion of tumor specific CD8+ T cells after prolonged tumor cell contact Stefanie Gross and Peter Walden |
| P80 | Immunophenotyping of peripheral blood T-cells in thoracic malignancies: The effect of cancer type and systemic chemotherapy on T-regulatory cells and other T-cell subsets Emily Grist, Georgios Ioannidis, Lindsey Low, Preethi Ganesan, Steven Harrison, Ann Mander, Andrew Bates, Anthony Williams and Christian Ottensmeier |
| P81 | Monitoring immune responses to a recombinant idiotypic vaccine: Optimization of the enzyme-linked immunospot assay (ELISpot) Marcelo Navarrete, Cristina Bertinetti, Kristina Mikesch, Hendrik Veelken |
| P82 | Improved TH1-polarisation of human monocyte-derived dendritic cells matured under serum-free conditions with novel highly purified TLR4-agonists Bernd Hildenbrand, Dirk Lorenzen, Barbara Sauer, Frank Neumann, Stefan F. Martin, Michael Huber, Clemens Unger, Marina A. Freudenberg, Chris Galanos, Marc Azemar |
| P83 | A phase I clinical trial with TriMix-Dendritic cell vaccine in advanced melanoma patients, preliminary results Kris Thielemans, Bart Neyns, Jurgen Corthals, Sandra Tuyaerts, Aude Bonehill |
| P84 | One-Pot, Mix-and-Read Peptide-MHC Tetramers Christian Leisner, Nina Loeth, Kasper Lamberth, Sune Justesen, Christina Sylvester-Hvid, Esben G. Schmidt, Mogens Claesson, Soren Buus, Anette Stryhn |
| P85 | Immunological monitoring of a phase II trial with Wilms tumor product 1 (WT1) peptide vaccination in patients with AML and MDS Anne Letsch, Ulrich Keilholz, Olga A. Elisseeva, Anne Marie Asemissen, Antonia Busse, Igor Wolfgang Blau, Wolf-Karsten Hofmann, Lutz Uharek, Yoshihiro Oka, Haruo Sugiyama, Eckhard Thiel, Carmen Scheibenbogen |
| P86 | Wnt5a sensitizes HEK293 cells for CTL-induced apoptosis by inducing a senescent phenotype Mathias Leber, Jennifer Goßmann, Peter R. Galle, Dennis Strand, Susanne Strand |
| P87 | The receptor for hyaluronic acid mediated motility (RHAMM): Characterization of an immunotherapeutical target which is associated with proliferation and shows prognostic value in B-cell chronic lymphocytic leukemia (B-CLL) patients and preliminary report on RHAMM-derived peptide vaccination trial for B-CLL patients Krzysztof Giannopoulos, Daniel Mertens, Malgorzata Kowal, Andreas Buehler, Thomas Barth, Irina Idler, Jochen Greiner, Paulina Wlasiuk, Sylwia Chocholska, Anna Dmoszynska, Jacek Rolinski, Hartmut Döhner, Stephan Stilgenbauer and Michael Schmitt |
| P88 | Induction of MAGE-specific donor T-cells for active immunotherapy in multiple myeloma Ines Möller, Hendrik Veelken, Leonora Houet |
| P89 | Generation of highly pure fusions of autologous tumor and antigen presenting cells Ulrike Klier, Tina Kottek, Ernst Klar, Michael Linnebacher |
| P90 | Characterization of MUC-1 specific T-cells in breast cancer patients and healthy donors Ana-Cristina Bâgu, Simone Kayser, Alexander Marmé, Stefan Stevanovic, Despina Rudolf, Diethelm Wallwiener, Brigitte Gückel |
| P91 | Neoepitopes generated by FLT3 internal tandem duplications (FLT3-ITDs) are recognized by autologous CD8+ and CD4+ T cells Claudine Graf, Florian Heidel, Stefan Stevanovic, Katja Busch, Christoph Huber, Thomas Fischer, Thomas Wölfel |
| P92 | Impact of hyper-IL-6 on transmigratory potency of peripheral blood lymphocytes isolated from melanoma patients immunized with gene modified tumor vaccine Dariusz Izycki, Katarzyna Gryska, Katarzyna Baksalary-Izycka, Jacek Mackiewicz, Andrzej Mackiewicz |
| P93 | RNA based T-cell receptor gene transfer into human T-lymphocytes Simone Thomas, Robert Popp, Eva Maria Strasser, Niels Schaft, Mirjam H. M. Heemskerk, Christoph Huber, Matthias Theobald, Ralf-Holger Voss |
| P94 | Activity of ERAPI/II aminopeptidases interferes with an effective presentation of the Melan-A/MART-1(26-35) epitope on melanoma cells Annette Paschen, Barbara Reimann, Tanja Lehmann, Kathrin Textoris-Taube, Sabrina Urban, Mingxia Song, Peter Henklein, Peter M. Kloetzel, Dirk Schadendorf, Ulrike Seifert |
| P95 | Detection and enrichment of antigen-specific naïve and effector/memory CD4+ and CD8+ T cells according to CD137 and CD154 expression Sonja Schmucker, Melanie Fahrendorff, Angela Hillenkötter, Sarah Hanselka, Anke Töpfer, Susanne Höher-Peters, Mario Assenmacher, and Anne Richter |
| P96 | Molecular mechanisms generating the irreversible HLA class I-low/-negative phenotype of malignant melanoma – chromosome 15 aberrations coincide with loss-of-function gene mutations, loss of transcription and posttranscriptional defects Antje Sucker, Sandra Striegel, Iris Moll, Hiltrud Schönhaber, Norbert Arens, Dirk Schadendorf, Annette Paschen |
| P97 | Immunogenicity of HLA-A1-restricted peptides derived from S100A4 in melanoma patients Valeska Hofmeister, Katharina Meder, David Schrama, Mads Hald Andersen, Eugene Lukanidin, Jürgen C. Becker |
| P98 | Comparison of immune responses after vaccination with tumor-peptide-loaded dendritic cells with or without prior denileukin diftitox treatment in metastasized malignant melanoma Michael Erdmann, Ina Haendle, Matthias Schmitt-Haendle, Waltraud Leisgang, Sonja Trump, Manuel Wiesinger, Eckhart Kaempgen, Beatrice Schuler-Thurner, Gerold Schuler |
| P99 | Evaluation of engraftment and graft-vs-host reactivity of ex vivo modified human donor T cell grafts in a chimeric NOD/SCID/IL2R?cnull transplantation model Marion Nonn, Marine Hörz, Shamsul Khan, Leonard Shultz, Rupert Handgretinger, Christoph Huber, Wolfgang Herr, Udo Frank Hartwig |
| P100 | Development of a peptide-vaccine targeting ovarian carcinomas and their vasculature Helen Hörzer, Stefan Stevanovic, Alexander Marmé, Peter Altevogt, Diethelm Wallwiener, Brigitte Gückel |
| P101 | withdrawn |
| P102 | |
| P103 | Efficient and preferential uptake of naked IVT-RNA by dendritic cells via macropinocytosis Mustafa Diken, Sebastian Kreiter, Abderraouf Selmi, Abdo Konur, Christoph Huber, Özlem Türeci, Ugur Sahin |
| P104 | Identification of preferentially targeted tumor-associated antigens in melanoma patients by mRNA stimulation of CD8+ blood lymphocytes Emmanuelle Wesarg, Serena Debo, Martina Fatho, Pierre van der Bruggen, Volker Lennerz, Thomas Wölfel |
| P105 | Proliferation of adoptively transferred donor T cells after Alemtuzumab-mediated T-cell depleted allogeneic stem cells can be monitored by CD52. Eva M. Wagner, T. Schmitt, J. Hemmerling, S. Wenzel, Abdo Konur, J. Bender, Christoph Huber, Wolfgang Herr, Ralf G. Meyer |
| P106 | Listeria monocytogenes as homing vector for tumor therapy Martin Heisig, Alexa Frentzen, Joachim Fensterle, Ulf R. Rapp, Werner Goebel |
| P107 | Inhibition of tumor growth by elimination of macrophages with a novel attenuated variant of Shigella flexneri serotype 5a Katharina Galmbacher, Christian Hotz, Martin Heisig, Jörg Wischhusen, Antoine Galmiche, Birgit Bergmann, Ivaylo Gentschev, Werner Goebel, Ulf R. Rapp and Joachim Fensterle |
| P108 | Functionality of a human gp100 specific single chain TCR can be achieved by its partial murinisation Beate Hauptrock, Ratna Sari Intan Poendl, Simone Thomas, Margarete Grabowski, Yasmin Djirsarai, Renate Engel, Christoph Huber, Ralf-Holger Voss, Matthias Theobald |
| P109 | Vaccination against metastatic cancer: Targeting of RhoC Lynn Wenandy, Rikke Bæk Sørensen, Inge Marie Svane, Mads Hald Andersen, and Per thor Straten |
| P110 | Pre-clinical development of drug-regulated, self-differentiating lentiviral vector-programmed dendritic cells for melanoma and leukemia immunotherapy Renata Stripecke, Mudita Pincha, Bala Sai Sundarasetty, Klaus H. Reichmuth, Farzin Farzaneh, Axel Schambach, Christopher Baum, Dirk Schadendorf, Eva Mischak-Weissinger and Arnold Ganser |
| P111 | UV irradiation enhances T cell responses induced by Transcutaneous Immunization with Imiquimod Pamela Aranda Lopez, Tobias Warger, Gerd Rechtsteiner, Hans-Christian Probst, Steffen Jung, Bernard Mallissen, Hansjörg Schild, and Markus P. Radsak |
| P112 | Expression of zonulin, c-kit and glial fibrillary acidic protein in human gliomas Heidegard Hilbig, Marco Skardelly, Franz-Paul Armbruster |
| P113 | Myeloid derived suppressor cells in patients with hepatocellular carcinoma induces CD4+CD25+FoxP3+ cells. Bastian Höchst, Michael P. Manns, Tim F. Greten, Firouzeh Korangy |
| P114 | Tankyrase 2 is a new candidate of pancreatic cancer antigen Fei Zhao, Benjamin Vermeer, Annette I. Garbe, Michael P. Manns, Firouzeh Korangy, Tim F. Greten |
